Plant disease control composition and its use

ABSTRACT

A plant disease control composition comprising a carboxamide compound represented by following formula (I), wherein R 1  represents a hydrogen atom or a methyl group, and R 2  represents a methyl group, a difluoromethyl group or a trifiuoromethyl group, and one or more dithiocarbamate compounds selected from group (A) consisting of mancozeb, maneb, thiram and zineb is provided by the present invention, and this composition has an excellent effect for controlling a plan disease.

TECHNICAL FIELD

The present invention relates to a plant disease control composition andits use.

BACKGROUND ART

Many compounds have been developed for controlling plant diseases andactually used (see, for example, PTL 1 and 2).

CITATION LIST Patent Literature

-   [PTL 1] : W086/02641-   [PTL 2] : W092/12970

SUMMARY OF INVENTION Technical Problem

An object of the present invention is to provide a composition having anexcellent effect for controlling plant disease.

Solution to Problem

The inventor of the present invention studied for seeking a compositionhaving an excellent effect for plant disease and found that acomposition comprising a carboxamide compound represented by followingformula (I) and one or more dithiocarbamate compounds selected fromfollowing group (A) has an excellent effect for controlling plantdisease and then completed the present invention.

The present invention provides the following [1] to [5].

A plant disease control composition comprising a carboxamide compoundrepresented by formula (I):

wherein

R¹ represents a hydrogen atom or a methyl group, and

R² represents a methyl group, a difluoromethyl group or atrifluoromethyl group,

and one or more dithiocarbamate compounds selected from group (A)consisting of mancozeb, maneb, thiram and zineb.

The plant disease control composition according to above [I], whereinthe weight ratio of the carboxamide compound to dithiocarbamatecompound(s) is from 0.01/1 to 1/1 of the carboxamide compound/thedithiocarbamate compound(s).

A method of controlling plant disease which comprises a step of treatinga plant or the soil where a plan grows with an effective amount of acarboxamide compound represented by formula (I):

wherein

R¹ represents a hydrogen atom or a methyl group, and

R² represents a methyl group, a difluoromethyl group or atrifluoromethyl group, and one or more dithiocarbamate compoundsselected from group (A) consisting of mancozeb, maneb, thiram and zineb.

The method of controlling plant disease according to above [3], whereinthe weight ratio of the carboxamide compound to dithiocarbamatecompound(s) is from 0.01/1 to 1/1 of the carboxamide compound/thedithiocarbamate compound(s).

The method of controlling plant disease according to the above [3] or[4], wherein the plant or the soil where a plan grows is wheat or thesoil where wheat grows, respectively.

Advantageous Effect of Invention

According to the present invention, various plant diseases can becontrolled.

DESCRIPTION OF EMBODIMENTS

The plant disease control composition of the present invention(hereinafter referred to as “composition”) comprises a carboxamidecompound represented by formula (I):

wherein

R¹ and R² represent the same meanings as defined in the above(hereinafter referred to as “carboxamide compound”),

and one or more dithiocarbamate compounds selected from group (A)consisting of mancozeb, maneb, thiram and zineb (hereinafter referred toas dithiocarbamate compounds).

The “carboxamide compound” are those as described in, for example,WO86/02641 or WO92/12970 and can be prepared by the method describedtherein.

Particular examples of the “carboxamide compounds” are as follows:

carboxamide compound represented by formula (1):

(hereinafter referred to as “carboxamide compound (1)”); carboxamidecompound represented by formula (2):

(hereinafter referred to as “carboxamide compound (2)”); carboxamidecompound represented by formula (3):

(hereinafter referred to as “carboxamide compound (3)”): carboxamidecompound represented by formula (4):

(hereinafter referred to as “carboxamide compound (4)”); carboxamidecompound represented by formula (5):

(hereinafter referred to as “carboxamide compound (5)”).

The “dithiocarbamate compounds” are known compound and described in, forexample, “THE PESTICIDE MANUAL—14th EDITION (published by BCPC) ISBN1901396142 and WO 95/27693. These compounds can be obtained from theproduct containing said compound in the market or can be synthesized bypublicly known method.

The weight ratio of the “carboxamide compound” to “dithiocarbamatecompounds” in the “composition” is usually from 0.001/1 to 500/1, andpreferably from 0.01/1 to 1/1 of “carboxamide compound”/“dithiocarbamatecompound(s)”.

Although the “composition” may be a mixture itself of a “carboxamidecompound” and “dithiocarbamate compound(s)”, the “composition” isusually prepared by mixing a “carboxamide compound”, “dithiocarbamatecompound(s)” and an inert carrier, and if necessary, by adding asurfactant and/or another auxiliary for formulation and by formulatingthe mixture into oil formulation, emulsifiable concentrate, flowableformulation, wettable powder, water dispersible granules, powder,granules, or the like.

The formulation, which is alone or by adding another inert component,can be used as a plant disease control agent.

The total content of a “carboxamide compound” and “dithiocarbamatecompound(s)” in a “composition” is usually from 0.1% to 99% by weight,preferably from 0.2% to 90% by weight, and more preferably from 1% to80% by weight.

Examples of the solid carriers used for the formulation include finepowder or granules of, for example, mineral materials such as kaolinclay, attapulgite, bentonite, montmorillonite, acid clay, pyrophillite,talc, diatomaceous earth and calcite; natural organic materials such ascorncob powder and walnut powder; synthesized organic materials such asurea; salts such as potassium carbonate and ammonium sulfate; syntheticinorganic materials such as synthesized hydrous silicon oxide.

Examples of the liquid carriers include aromatic hydrocarbons such asxylene, alkylbenzene and methylnaphthalene; alcohols such as 2-propanol,ethylene glycol, propylene glycol and ethylene glycol mono-ethyl ether;ketones such as acetone, cyclohexanone and isophorone; vegetable oilssuch as soybean oil and cotton seed oil; petrolic aliphatichydrocarbons; esters; dimethylsulfoxide; acetonitrile; and water.Examples of the surfactants include anionic surfactants such as alkylsulfate ester salts, alkylarylsulfonate salts, dialkylsulfosuccinatesalts, polyoxyethylene alkylaryl ether phosphoric acid ester salts,lignin sulfonate and naphthalene sulfonate formaldehyde polycondensedproducts; non-ionic surfactants such as polyoxyethylene alkyl arylethers, polyoxyethylene alkyl polyoxypropylene block copolymers andsorbitan fatty acid esters; and cationic surfactants such as alkyltrimethyl ammonium salts. Examples of the other auxiliaries forformulation include water-soluble polymers such as polyvinyl alcohol andpolyvinylpyrrolidone; polysaccharides such as gum arabic, alginic acidand its salt, CMC (carboxymethylcellulose) and xanthan gum; inorganicmaterials such as aluminum magnesium silicate and alumina sol;preservatives; coloring agents; and stabilizers such as PAP (acidicisopropyl phosphate) and BHT.

The “composition” can be also prepared by formulating a “carboxamidecompound” and “dithiocarbamate compound(s)” according to the method asdescribed in the above, and then making the formulations or theirdiluents.

The “composition” can be used for protecting plant from plant disease.

Examples of plant diseases which can be controlled by the “composition”include the followings.

Rice diseases: Magnaporthe grisea, Cochliobolus miyabeanus, Rhizoctoniasolani, Gibberella fujikuroi;

Wheat diseases: Erysiphe graminis, Fusarium graminearum, F. avenaceum,F. culmorum, Microdochium nivale, Puccinia striiformis, P. graminis, P.recondita, Micronectriella nivale, Typhula sp., Ustilago tritici,Tilletia caries, Pseudocercosporella herpotrichoides, Mycosphaerellagraminicola, Stagonospora nodorum, Pyrenophora tritici-repentis;

Barley diseases:

Erysiphe graminis, Fusarium graminearum, F. avenaceum, F. culmorum,Microdochium nivale, Puccinia striiformis, P. graminis, P. hordei,Ustilago nuda, Rhynchosporium secalis, Pyrenophora teres, Cochliobolussativus, Pyrenophora graminea, Rhizoctonia solani;

Maize diseases: Ustilago maydis, Cochliobolus heterostrophus,Gloeocercospora sorghi, Puccinia polysora, Cercospora zeae-maydis,Rhizoctonia solani;

Citrus diseases: Diaporthe citri, Elsinoe fawcetti, Penicilliumdigitatum, P. italicum, Phytophthora parasitica, Phytophthoracitrophthora;

Apple diseases: Monilinia mali, Valsa ceratosperma, Podosphaeraleucotricha, Alternaria alternata apple pathotype, Venturia inaequalis,Colletotrichum acutatum, Phytophtora cactorum;

Pear diseases: Venturia nashicola, V. pirina, Alternaria alternataJapanese pear pathotype, Gymnosporangium haraeanum, Phytophtoracactorum;

Peach diseases: Monilinia fructicola, Cladosporium carpophilum,Phomopsis sp.;

Grape diseases: Elsinoe ampelina, Glomerella cingulata, Uninula necator,Phakopsora ampelopsidis, Guignardia bidwellii, Plasmopara viticola;

Persimmon diseases: Gloesporium kaki, Cercospora kaki, Mycosphaerelanawae;

Gourd diseases: Colletotrichum lagenarium, Sphaerotheca fuliginea,Mycosphaerella melonis, Fusarium oxysporum, Pseudoperonospora cubensis,Phytophthora sp., Pythium sp.;

Tomato diseases: Alternaria solani, Cladosporium fulvum, Phytophthorainfestans;

Eggplant diseases: Phomopsis vexans, Erysiphe cichoracearum;Brassicaceous vegetable diseases: Alternaria japonica, Cercosporellabrassicae, Plasmodiophora brassicae, Peronospora parasitica;

Welsh onion diseases: Puccinia allii, Peronospora destructor;

Soybean diseases: Cercospora kikuchii, Elsinoe glycines, Diaporthephaseolorum var. sojae, Septoria glycines, Cercospora sojina, Phakopsorapachyrhizi, Phytophthora sojae, Rhizoctonia solani, Corynesporacasiicola, Sclerotinia sclerotiorum;

Kidney bean diseases: Colletrichum lindemthianum;

Peanut diseases: Cercospora personata, Cercospora arachidicola,Sclerotium rolfsii;

Pea diseases pea: Erysiphe pisi;

Potato diseases: Alternaria solani, Phytophthora infestans, Phytophthoraerythroseptica, Spongospora subterranean, f. sp. Subterranean;

Strawberry diseases: Sphaerotheca humuli, Glomerella cingulata;

Tea diseases: Exobasidium reticulatum, Elsinoe leucospila,Pestalotiopsis sp., Colletotrichum theae-sinensis;

Tobacco diseases: Alternaria longipes, Erysiphe cichoracearum,Colletotrichum tabacum, Peronospora tabacina, Phytophthora nicotianae;

Rapeseed diseases: Sclerotinia sclerotiorum, Rhizoctonia solani;

Cotton diseases: Rhizoctonia solani;

Beet diseases: Cercospora beticola, Thanatephorus cucumeris,Thanatephorus cucumeris, Aphanomyces cochlioides;

Rose diseases: Diplocarpon rosae, Sphaerotheca pannosa, Peronosporasparsa;

Diseases of chrysanthemum and asteraceae: Bremia lactuca, Septoriachrysanthemiindici, Puccinia horiana;

Diseases of various plants: Pythium aphanidermatum, Pythium debarianum,Pythium graminicola, Pythium irregulare, Pythium ultimum, Botrytiscinerea, Sclerotinia sclerotiorum;

Radish diseases: Alternaria brassicicola;

Zoysia diseases: Sclerotinia homeocarpa, Rhizoctonia solani;

Banana diseases: Mycosphaerella fijiensis, Mycosphaerella musicola;

Sunflower diseases: Plasmopara halstedii;

Seed diseases or diseases in the initial stage of growth of variousplants caused by Aspergillus spp., Penicillium spp., Fusarium spp.,Gibberella spp., Tricoderma spp., Thielaviopsis spp., Rhizopus spp.,Mucor spp., Corticium spp., Rhoma spp., Rhizoctonia spp., Diplodia spp.,or the like;

Virus diseases of various plants mediated by Polymixa spp., Olpidiumspp., or the like.

Examples of the plants for which the “composition” can be used includethe followings:

Agricultural crops: maize, rice, wheat, barley, rye, oat, sorghum,cotton, soybean, peanut, buckwheat, sugar beet, rapeseed, sunflower,sugar cane, tobacco, and the like;

Vegetables: Solanaceous vegetables (eggplant, tomato, green pepper, hotpepper, potato, etc.), Cucurbitaceous vegetables (cucumber, pumpkin,zucchini, watermelon, melon, squash, etc.); Cruciferous vegetables(radish, turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, brownmustard, broccoli, cauliflower, etc.), Asteraceous vegetables (burdock,garland chrysanthemum, artichoke, lettuce, etc.), Liliaceous vegetables(Welsh onion, onion, garlic, asparagus, etc.), Umbelliferous vegetables(carrot, parsley, celery, parsnip, etc.), Chenopodiaceous vegetables(spinach, chard, etc.), Lamiaceous vegetables (Japanese basil, mint,basil, etc.), strawberry, sweet potato, yam, aroid, and the like;

Flowering plants;

Ornamental foliage plants;

Turf;

Fruit trees: pome fruits (apple, common pear, Japanese pear, Chinesequince, quince, etc.), stone fruits (peach, plum, nectarine, Japaneseplum, cherry, apricot, prune, etc.), citrus (mandarin, orange, lemon,lime, grapefruit, etc.), nuts (chestnut, walnut, hazel nut, almond,pistachio, cashew nut, macadamia nut, etc.), berry fruits (blueberry,cranberry, blackberry, raspberry, etc.), grape, persimmon, olive,loquat, banana, coffee, date, coconut palm, and the like;

Trees other than fruit trees: tea, mulberry, flowering trees, streettrees (ash tree, birch, dogwood, eucalyptus, ginkgo, lilac, maple tree,oak, poplar, cercis, Chinese sweet gum, plane tree, zelkova, Japanesearborvitae, fir tree, Japanese hemlock, needle juniper, pine, spruce,yew), and the like.

The above-described plants may be those having resistance imparted bygenetic engineering technique.

Among the above plants, the “composition” is expected to have excellentcontrolling effect particularly to plant diseases caused in wheat.

Among the above plant diseases, the diseases in wheat to whichespecially excellent effect of the “composition” can be expected arePuccinia striiformis, P. graminis, P. recondita, Mycosphaerellagraminicola, Stagonospora nodorum, Pyrenophora triticirepentis, and thelike.

Following compositions exemplify embodiments of the “composition”:

-   -   a composition comprising “carboxamide compound (1)” and        mancozeb;    -   a composition comprising “carboxamide compound (1)” and maneb;    -   a composition comprising “carboxamide compound (1)” and thiram;    -   a composition comprising “carboxamide compound (1)” and zineb;    -   a composition comprising “carboxamide compound (2)” and        mancozeb;    -   a composition comprising “carboxamide compound (2)” and maneb;    -   a composition comprising “carboxamide compound (2)” and thiram;    -   a composition comprising “carboxamide compound (2)” and zineb;    -   a composition comprising “carboxamide compound (3)” and        mancozeb;    -   a composition comprising “carboxamide compound (3)” and maneb;    -   a composition comprising “carboxamide compound (3)” and thiram;    -   a composition comprising “carboxamide compound (3)” and zineb;    -   a composition comprising “carboxamide compound (4)” and        mancozeb;    -   a composition comprising “carboxamide compound (4)” and maneb;    -   a composition comprising “carboxamide compound (4)” and thiram;    -   a composition comprising “carboxamide compound (4)” and zineb;    -   a composition comprising “carboxamide compound (5)” and        mancozeb;    -   a composition comprising “carboxamide compound (5)” and maneb;    -   a composition comprising “carboxamide compound (5)” and thiram;    -   a composition comprising “carboxamide compound (5)” and zineb;    -   a composition comprising “carboxamide compound (1)” and mancozeb        in which the weight ratio of “carboxamide compound (1)” to        mancozeb is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (1)” and maneb in        which the weight ratio of “carboxamide compound (1)” to maneb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (1)” and thiram        in which the weight ratio of “carboxamide compound (1)” to        thiram is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (1)” and zineb in        which the weight ratio of “carboxamide compound (1)” to zineb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (2)” and mancozeb        in which the weight ratio of “carboxamide compound (2)” to        mancozeb is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (2)” and maneb in        which the weight ratio of “carboxamide compound (2)” to maneb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (2)” and thiram        in which the weight ratio of “carboxamide compound (2)” to        thiram is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (2)” and zineb in        which the weight ratio of “carboxamide compound (2)” to zineb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (3)” and mancozeb        in which the weight ratio of “carboxamide compound (3)” to        mancozeb is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (3)” and maneb in        which the weight ratio of “carboxamide compound (3)” to maneb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (3)” and thiram        in which the weight ratio of “carboxamide compound (3)” to        thiram is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (3)” and zineb in        which the weight ratio of “carboxamide compound (3)” to zineb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (4)” and mancozeb        in which the weight ratio of “carboxamide compound (4)” to        mancozeb is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (4)” and maneb in        which the weight ratio of “carboxamide compound (4)” to maneb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (4)” and thiram        in which the weight ratio of “carboxamide compound (4)” to        thiram is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (4)” and zineb in        which the weight ratio of “carboxamide compound (4)” to zineb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (5)” and mancozeb        in which the weight ratio of “carboxamide compound (5)” to        mancozeb is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (5)” and maneb in        which the weight ratio of “carboxamide compound (5)” to maneb is        0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (5)” and thiram        in which the weight ratio of “carboxamide compound (5)” to        thiram is 0.01/1 to 1/1;    -   a composition comprising “carboxamide compound (5)” and zineb in        which the weight ratio of “carboxamide compound (5)” to zineb is        0.01/1 to 1/1;

The method for controlling plant disease (hereinafter referred to as“controlling method”) can be carried out by treating a plant or the soilwhere a plan grows with an effective amount of a “carboxamide compound”and “dithiocarbamate compound(s)”.

The part of plant to be treated is stem and leaf of a plant, seed orbulb of a plant, and the bulb means bulb, corm, rootstock, tuber,tuberous root and rhizophore.

In the “controlling method”, the treatment of a plant or the soil wherea plan grows with a “carboxamide compound” and “dithiocarbamatecompound(s)” can be carried out separately at the same timing, but thetreatment is usually carried out by using a “composition” in light ofconvenience.

In the “controlling method”, the treatment with a “carboxamide compound”and “dithiocarbamate compound(s)” is, for example, stems and leavesapplication, soil application, roots application or seeds application.

Examples of the stems and leaves application include a treatment forsurface of cultivated plant by a stem and leave spray or a stem and treespray.

Examples of the root application include a method of dipping a wholeplant or root of a plant into a liquid containing a “carboxamidecompound” and “dithiocarbamate compound(s)” and a method of sticking asolid preparation comprising a “carboxamide compound”, “dithiocarbamatecompound(s)” and a solid carrier onto root of a plant.

Examples of the soil application include a method of spraying a“composition” onto the soil, a method of mixing a “composition” with asoil and a method of irrigating a “composition” into the soil.

Examples of the seed application include a method of treating seeds orbulbs of a plant to be protected from a plant disease with a“composition”. Particularly, the application can be carried out byspraying a suspension of a “composition” to the surface of seeds orbulbs, or by spreading wettable powder, emulsifiable concentrate orflowable formulation itself or a mixture thereof with a small amount ofwater on the seeds or the bulbs, or by dipping the seeds into a solutionof a “composition” for a prescribed time, or by film coating applicationor pellet coating application.

The amount of a “carboxamide compound” and “dithiocarbamate compound(s)”used in the “controlling method” is different depending on the kind of aplant to be treated, the kind of a plant disease to be controlled andits frequency, the kind of a formulation, timing of treatment, method oftreatment, place of treatment, weather condition, and the like.

When a “composition” is applied to stems and/or leaves of a plant or tothe soil where a plan grows, the total amount of a “carboxamidecompound” and “dithiocarbamate compound(s)” is usually from b 1 g to 500g/1000 m², preferably from 2 g to 200 g/1000 m², and more preferablyfrom 10 g to 100 g/1000 m².

When a “composition” is applied to seeds of a plant, the total amount ofa “carboxamide compound” and “dithiocarbamate compound(s)” is usuallyfrom 0.001 g to 10 g/1 kg of the seeds, and preferably from 0.01 g to 1g/1 kg of the seeds.

An emulsifiable concentrate, wettable powder or flowable formulation isusually used by diluting the formulation with water and spraying thediluted formulation. In this case, the concentration of a “carboxamidecompound” and “dithiocarbamate compound(s)” in total of the dilutedformulation is usually from 0.0005 to 2% by weight and preferably from0.005 to 1% by weight.

A powder formulation, granule formulation, and the like is usually usedwithout dilution.

EXAMPLE

The present invention is further explained in detail with FormulationExamples and Test Examples. However, the present invention is notlimited by the following Examples.

In the following Examples, “part” means “part by weight” unlessotherwise provided.

Formulation Example 1

One of “carboxamide compounds” (1) to (5) (2 part), mancozeb (8 parts),a mixture of white carbon and polyoxyethylene alkyl ether sulfateammonium salt (weight ratio 1:1) (35 parts) and water (55 parts) aremixed and milled by wet-milling method to give each of formulations,respectively.

Formulation Example 2

One of “carboxamide compounds” (1) to (5) (2 part), maneb (8 parts), amixture of white carbon and polyoxyethylene alkyl ether sulfate ammoniumsalt (weight ratio 1:1) (35 parts) and water (55 parts) are mixed andmilled by wet-milling method to give each of formulations, respectively.

Formulation Example 3

One of “carboxamide compounds” (1) to (5) (2 part), thiram (8 parts), amixture of white carbon and polyoxyethylene alkyl ether sulfate ammoniumsalt (weight ratio 1:1) (35 parts) and water (55 parts) are mixed andmilled by wet-milling method to give each of formulations, respectively.

Formulation Example 4

One of “carboxamide compounds” (1) to (5) (2 part), zineb (8 parts), amixture of white carbon and polyoxyethylene alkyl ether sulfate ammoniumsalt (weight ratio 1:1) (35 parts) and water (55 parts) are mixed andmilled by wet-milling method to give each of formulations, respectively.

Formulation Example 5

One of “carboxamide compounds” (1) to (5) (3 parts), mancozeb (12parts), sorbitan tri-oleate (1.5 parts) and an aqueous solution (28.5parts) containing polyvinyl alcohol (2 parts) are mixed and the mixtureis milled by wet-milling method. To the milled mixture is added anaqueous solution (45 parts) containing xanthan gum (0.05 parts) andaluminum magnesium silicate (0.1 part), and further propylene glycol (10parts) is added to the mixture. The resultant mixture is mixed bystirring to give each of formulations, respectively.

Formulation Example 6

One of “carboxamide compounds” (1) to (5) (3 parts), maneb (12 parts),sorbitan trioleate (1.5 parts) and an aqueous solution (28.5 parts)containing polyvinyl alcohol (2 parts) are mixed and the mixture ismilled by wet-milling method. To the milled mixture is added an aqueoussolution (45 parts) containing xanthan gum (0.05 parts) and aluminummagnesium silicate (0.1 part), and further propylene glycol (10 parts)is added to the mixture. The resultant mixture is mixed by stirring togive each of formulations, respectively.

Formulation Example 7

One of “carboxamide compounds” (1) to (5) (3 parts), thiram (12 parts),sorbitan trioleate (1.5 parts) and an aqueous solution (28.5 parts)containing polyvinyl alcohol (2 parts) are mixed and the mixture ismilled by wet-milling method. To the milled mixture is added an aqueoussolution (45 parts) containing xanthan gum (0.05 parts) and aluminummagnesium silicate (0.1 part), and further propylene glycol (10 parts)is added to the mixture. The resultant mixture is mixed by stirring togive each of formulations, respectively.

Formulation Example 8

One of “carboxamide compounds” (1) to (5) (3 parts), zineb (12 parts),sorbitan trioleate (1.5 parts) and an aqueous solution (28.5 parts)containing polyvinyl alcohol (2 parts) are mixed and the mixture ismilled by wet-milling method. To the milled mixture is added an aqueoussolution (45 parts) containing xanthan gum (0.05 parts) and aluminummagnesium silicate (0.1 part), and further propylene glycol (10 parts)is added to the mixture. The resultant mixture is mixed by stirring togive each of formulations, respectively.

Formulation Example 9

One of “carboxamide compounds” (1) to (5) (1 part), mancozeb (4 parts),synthesized hydrous silicon oxide (1 part), calcium ligninsulfonate (2parts), bentonite (30 parts) and kaolin clay (62 parts) are thoroughlymixed and milled. Water is added to the mixture and the mixture issufficiently kneaded, granulated and then dried to give each offormulations, respectively.

Formulation Example 10

One of “carboxamide compounds” (1) to (5) (1 part), maneb (4 parts),synthesized hydrous silicon oxide (1 part), calcium ligninsulfonate (2parts), bentonite (30 parts) and kaolin clay (62 parts) are thoroughlymixed and milled. Water is added to the mixture and the mixture issufficiently kneaded, granulated and then dried to give each offormulations, respectively.

Formulation Example 11

One of “carboxamide compounds” (1) to (5) (1 part), thiram (4 parts),synthesized hydrous silicon oxide (1 part), calcium ligninsulfonate (2parts), bentonite (30 parts) and kaolin clay (62 parts) are thoroughlymixed and milled. Water is added to the mixture and the mixture issufficiently kneaded, granulated and then dried to give each offormulations, respectively.

Formulation Example 12

One of “carboxamide compounds” (1) to (5) (1 part), zineb (4 parts),synthesized hydrous silicon oxide (1 part), calcium ligninsulfonate (2parts), bentonite (30 parts) and kaolin clay (62 parts) are thoroughlymixed and milled. Water is added to the mixture and the mixture issufficiently kneaded, granulated and then dried to give each offormulations, respectively.

Formulation Example 13

One of “carboxamide compounds” (1) to (5) (12.5 parts), mancozeb (37.5parts), calcium ligninsulfonate (3 parts), sodium lauryl sulfate (2parts) and synthesized hydrous silicon oxide (45 parts) are thoroughlymixed and milled to give each of formulations, respectively.

Formulation Example 14

One of “carboxamide compounds” (1) to (5) (3 parts), mancozeb (2 parts),kaolin clay (85 parts) and talc (10 parts) are thoroughly mixed andmilled to give each of formulations, respectively.

Test Examples using each of the “compositions” are shown in thefollowing.

Test Example 1

Each plastic pot was filled with soil, and seeds of wheat (variety:Apogee) were seeded in the soil followed by growing for 14 days in agreenhouse. Test compounds were formulated into formulations accordingto Formulation Example 5, and the formulation was diluted with water toprescribed concentration. Foliar application of the dilution was carriedout so that dilution would adhere to surface of leaves of the wheatsufficiently. After spraying, the plant was air-dried and two daysafter, the plant was inoculated by spraying aqueous suspension ofconidiospores of Mycosphaerella graminicola (about 1,000,000/ml). Afterthe inoculation, the plants were placed under high humidity condition at18° C. for 3 days, taken out from the high humidity condition and thenplaced in a thermostatic room at 18° C. for 14 days (hereinafterreferred to as “treated plot”). Thereafter, the lesion area byMycosphaerella graminicola was investigated.

On the other hand, wheat was grown in the same way as above “treatedplot” except for that the dilution of the test compound was not appliedto the stems and leaves (hereinafter referred to as “non-treated plot”).The lesion area by Mycosphaerella graminicola was investigated as above“treated plot”.

On the basis of the above lesion areas in “treated plot” and“non-treated plot”, efficacy in “treated plot” was evaluated by thefollowing calculation formula (1). The results are shown in Table 1 andTable 2.Efficacy (%)=[1−(lesion area in “treated plot”/lesion area in“non-treated plot”)]×100  Calculation Formula (1)

TABLE 1 “carboxamide compound (1)” mancozeb [ppm] [ppm] efficacy (%) 50700 100

TABLE 2 “carboxamide compound (5)” mancozeb [ppm] [ppm] efficacy (%) 50700 100

INDUSTRIAL APPLICABILITY

A plant disease control composition comprising a “carboxamide compound”represented by formula (I) and a dithiocarbamate compound is useful forcontrolling plant disease.

The invention claimed is:
 1. A plant disease control compositioncomprising a carboxamide compound represented by formula (1):

and mancozeb, wherein the weight ratio of the carboxamide compound tomancozeb is from 0.01/1 to 1/1 of the carboxamide compound/mancozeb. 2.A method of controlling plant disease which comprises a step of treatinga plant or the soil where a plant grows with an effect amount of acarboxamide compound represented by formula (1):

and mancozeb, wherein the weight ratio of the carboxamide compound tomancozeb is from 0.01/1 to 1/1 of the carboxamide compound/mancozeb. 3.The method of controlling plant disease according to claim 2 wherein theplant or the soil where a plant grows is wheat or the soil where wheatgrows, respectively.